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Bleomycin-induced pulmonary fibrosis model
1.Research Background Pulmonary fibrosis is a chronic, progressive lung disease characterized by the proliferation of fibroblasts and excessive accumulation of extracellular matrix, accompanied by inflammatory damage and structural destruction of lung tissue. This condition represents the end-sta
2024-09-05
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Exoskeleton partially coated with stem cells for infarcted myocardium repair
Over the past few decades, many efforts have been made in tissue engineering, with cell-based therapies covering nerve, bone, cartilage and heart tissue. In particular, stem cells have complex functions, including homing, exocrine capacity, signal transduction, and regeneration with low immunoge
2024-07-30
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Explanation of cytokines: the interleukin family
1, The Past and present Life of interleukin There is a group of protein molecules in the human body that are unknown but play a vital role in the immune system. They are interleukins (IL), Interleukins are a type of lymphokine produced by a variety of cells and interacting between l
2024-07-30
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Animal modeling-pancreatic cancer liver metastasis model Background introduction
The comprehensive treatment of pancreatic cancer, mainly surgery, is not effective, and metastasis occurs early after surgery. The main cause of death from pancreatic cancer is metastatic disease caused by pancreatic cancer, and the most common site is the liver. Establishing a good ani
2024-07-18
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Animal modeling-nude mouse tumor model
The nude mouse tumor model (Cell Derived Xenograft, CDX) is a commonly used tumor research model, which involves directly injecting tumor cells cultured in vitro into immunodeficient mice (usually nude mice, i.e. BALB/c-nu mice) to simulate the biological characteristics of human tumors, including t
2024-07-10
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Ovalbumin(OVA) induced asthma model
Animal Model - Asthma Model From ELK Biotech Wechat public account Ovalbumin (OVA) induced asthma model Background Asthma (Asthma) is a chronic airway inflammatory disease characterized by variable airflow obstruction, airway hyperreactivity (AHR), and airway inflammation. The m
2024-07-01
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Model of chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a common respiratory system disease with high incidence of a disease and mortality, which may lead to progressive pulmonary dysfunction, respiratory failure and cor pulmonale. In order to study the pathogenesis of COPD and find effective treatm
2024-06-20
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Cytokine Overview
I. Introduction Cytokine (CK) is a kind of small molecule opal with a wide range of biological activities. It is synthesized and secreted by immune cells (such as monocytes, macrophages, T cells, B cells, NK cells, etc.) and some non-immune cells (endothelial cells, epidermal cells, fibroblasts,
2024-06-12