| Product name: |
DCT rabbit pAb |
| Reactivity: |
Human;Rat;Mouse |
| Alternative Names: |
L-dopachrome tautomerase (DCT;DT;EC 5.3.3.12;L-dopachrome Delta-isomerase;Tyrosinase-related protein 2;TRP-2;TRP2) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000 |
| Immunogen: |
Synthetic peptide from human protein at AA range: 232-304 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
59kD |
| GeneID: |
1638 |
| Human Swiss-Prot No: |
P40126 |
| Cellular localization: |
Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. . |
| Background: |
catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex., |
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