PDK1 rabbit pAb

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PDK1 rabbit pAb

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ES3168

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PDK1 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	PDK1; PDHK1; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; mitochondrial; Pyruvate dehydrogenase kinase isoform 1
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	Synthesized peptide derived from PDK1 . at AA range: 80-160
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	50kD
GeneID:	5163
Human Swiss-Prot No:	Q15118
Cellular localization:	Mitochondrion matrix .
Background:	Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],

Western Blot analysis of various cells using PDK1 Polyclonal Antibody
Western Blot analysis of Hela cells using PDK1 Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).