Product name: | Kv11.3 rabbit pAb |
Reactivity: | Human;Rat;Mouse |
Alternative Names: | Potassium voltage-gated channel subfamily H member 7 (Ether-a-go-go-related gene potassium channel 3;ERG-3;Eag-related protein 3;Ether-a-go-go-related protein 3;hERG-3;Voltage-gated potassium channel subunit Kv11.3) |
Source: | Rabbit |
Dilutions: | WB 1:1000-2000, IHC 1:100-200 |
Immunogen: | Synthetic Peptide of Kv11.3. AA range 1130-1180 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 83135kD |
GeneID: | 90134 |
Human Swiss-Prot No: | Q9NS40 |
Cellular localization: | Membrane; Multi-pass membrane protein. |
Background: | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008], |