$148.00/50µL $248.00/100µL
50 µL | $148.00 |
100 µL | $248.00 |
Product name: | PROC (light chain, Cleaved-Leu179) rabbit pAb |
Reactivity: | Human;Rat;Mouse; |
Alternative Names: | Vitamin K-dependent protein C (EC 3.4.21.69;Anticoagulant protein C;Autoprothrombin IIA;Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide] |
Source: | Rabbit |
Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
Immunogen: | Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179) |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 17 45kD |
GeneID: | 5624 |
Human Swiss-Prot No: | P04070 |
Cellular localization: | Secreted . Golgi apparatus . Endoplasmic reticulum . |
Background: | This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009], |