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CE112 rabbit pAb
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ES17530
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CE112 rabbit pAb
Reactivity: Human; Mouse
Alternative Names: Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human CE112 AA range: 475-525
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 105kD
GeneID: 201134
Human Swiss-Prot No: Q8N8E3
Cellular localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .
Background: This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],