Product name: |
GP-39 rabbit pAb |
Reactivity: |
Human;Rat;Mouse; |
Alternative Names: |
Chitinase-3-like protein 1 (39 kDa synovial protein;Cartilage glycoprotein 39;CGP-39;GP-39;hCGP-39;YKL-40) |
Source: |
Rabbit |
Dilutions: |
IHC-p 1:50-200, WB 1:500-2000 |
Immunogen: |
Synthesized peptide derived from human GP-39 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
42kD |
GeneID: |
1116 |
Human Swiss-Prot No: |
P36222 |
Cellular localization: |
Secreted, extracellular space . Cytoplasm . Cytoplasm, perinuclear region . Endoplasmic reticulum . |
Background: |
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009], |