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PLEK2 rabbit pAb
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ES14065
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50 µL $148.00
100 µL $248.00
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Overview

Product name: PLEK2 rabbit pAb
Reactivity: Human; Mouse
Alternative Names: Pleckstrin-2
Source: Rabbit
Dilutions: WB 1:500-2000
Immunogen: Synthesized peptide derived from human PLEK2 AA range: 5-55
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 26499
Human Swiss-Prot No: Q9NYT0
Cellular localization: Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Background: The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015],