Synthesized peptide derived from human protein . at AA range: 350-430
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
103kD
GeneID:
219699
Human Swiss-Prot No:
Q8IZJ1
Cellular localization:
Cell membrane ; Single-pass type I membrane protein . Membrane raft . Associated with lipid rafts. .
Background:
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
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