Synthesized peptide derived from human protein . at AA range: 170-250
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
61kD
GeneID:
153562
Human Swiss-Prot No:
Q8N4S9
Cellular localization:
Cell membrane ; Multi-pass membrane protein . Cell junction, tight junction . Located at tricellular contacts. .
Background:
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
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