Product name: | NEIL2 rabbit pAb |
Reactivity: | Human;Mouse |
Source: | Rabbit |
Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
Immunogen: | Synthesized peptide derived from part region of human protein |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 36kD |
GeneID: | 252969 |
Human Swiss-Prot No: | Q969S2 |
Cellular localization: | Nucleus . |
Background: | NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM, Mar 2008], |