CHD8 rabbit pAb

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CHD8 rabbit pAb

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ES9540

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	CHD8 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Source:	Rabbit
Dilutions:	IHC-p 1:50-300
Immunogen:	Synthesized peptide derived from part region of human protein
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	283kD
GeneID:	57680
Human Swiss-Prot No:	Q9HCK8
Cellular localization:	Nucleus . Localizes to the promoter regions of several CTNNB1-responsive genes. Also present at known CTCF target sites. .
Background:	This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],

Immunohistochemical analysis of paraffin-embedded human spleen. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).
Western Blot analysis of various,using primary antibody at 1:1000 dilution. Secondary antibody(catalog#:RS23920) was diluted at 1:10000