Synthesized peptide derived from human protein . at AA range: 720-800
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
185kD
GeneID:
5927
Human Swiss-Prot No:
P29375
Cellular localization:
Nucleus, nucleolus . Nucleus . Occupies promoters of genes involved in RNA metabolism and mitochondrial function. .
Background:
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013],
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