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SMG9 rabbit pAb
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ES9092
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50 µL $148.00
100 µL $248.00
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Overview

Product name: SMG9 rabbit pAb
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 70-150
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 57kD
GeneID: 56006
Human Swiss-Prot No: Q9H0W8
Cellular localization: intracellular,cytosol,
Background: SMG9, nonsense mediated mRNA decay factor(SMG9) Homo sapiens This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features. [provided by RefSeq, Jul 2016],