Synthesized peptide derived from human protein . at AA range: 260-340
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
82kD
GeneID:
4520
Human Swiss-Prot No:
Q14872
Cellular localization:
Nucleus . Cytoplasm . Translocation to the nucleus is induced by metals. .
Background:
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008],
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