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AKAP6 rabbit pAb
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ES9054
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AKAP6 rabbit pAb
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilutions: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human protein . at AA range: 30-110
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 255kD
GeneID: 9472
Human Swiss-Prot No: Q13023
Cellular localization: Sarcoplasmic reticulum. Nucleus membrane. In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.
Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008],