Products

NUAK1 rabbit pAb
One-click to copy product information
ES8955
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: NUAK1 rabbit pAb
Reactivity: Human;Mouse
Source: Rabbit
Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 530-610
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 72kD
GeneID: 9891
Human Swiss-Prot No: O60285
Cellular localization: Nucleus . Cytoplasm .
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by PKB/AKT1 during glucose starvation. Activated by phosphorylation on Thr-211 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Involved in tolerance to glucose starvation. Phosphorylates ATM. Suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed at high levels in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung and liver.,