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AGTR1 rabbit pAb
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ES8937
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50 µL $148.00
100 µL $248.00
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Overview

Product name: AGTR1 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from human AGTR1 Polyclonal
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 41kD
GeneID: 185
Human Swiss-Prot No: P30556
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012],