Products

MOT4 rabbit pAb
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ES8930
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: MOT4 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized peptide derived from human MOT4 Polyclonal
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID: 9123
Human Swiss-Prot No: O15427
Cellular localization: Cell membrane; Multi-pass membrane protein.
Background: Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008],