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Granzyme B rabbit pAb
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ES8917
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Granzyme B rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Granzyme B (EC 3.4.21.79;C11;CTLA-1;Cathepsin G-like 1;CTSGL1;Cytotoxic T-lymphocyte proteinase 2;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;HLP;SECT;T-cell serine protease 1-3E)
Source: Rabbit
Dilutions: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from human Granzyme B Polyclonal AA range: 81-130
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 38kD
GeneID: 3002
Human Swiss-Prot No: P10144
Cellular localization: Secreted . Cytolytic granule . Delivered into the target cell by perforin (PubMed:20038786). .
Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016],