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MAP4 rabbit pAb
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ES8897
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100 µL $248.00
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Overview

Product name: MAP4 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Microtubule-associated protein 4 (MAP-4)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from human MAP4 Polyclonal
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 85kD
GeneID: 4134
Human Swiss-Prot No: P27816
Cellular localization: Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center . Recruitment to microtubule is inhibited by microtubules polyglutamylation. .
Background: The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],