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SYK rabbit pAb(N-ternal)
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ES8890
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50 µL $148.00
100 µL $248.00
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Overview

Product name: SYK rabbit pAb(N-ternal)
Reactivity: Human;Mouse;Rat
Alternative Names: Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from human SYK
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 72kD
GeneID: 6850
Human Swiss-Prot No: P43405
Cellular localization: Cell membrane . Cytoplasm, cytosol .
Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],