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C8 α rabbit pAb
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ES8864
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50 µL $148.00
100 µL $248.00
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Overview

Product name: C8 α rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Complement component C8 alpha chain (Complement component 8 subunit alpha)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from human C8 α. at AA range: 201-250
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID: 731
Human Swiss-Prot No: P07357
Cellular localization: Secreted. Cell membrane; Multi-pass membrane protein. Secreted as soluble protein. Inserts into the cell membrane of target cells.
Background: C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008],