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Parafibromin rabbit pAb
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ES8836
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Parafibromin rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from human Parafibromin. at AA range: 51-100
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID: 79577
Human Swiss-Prot No: Q6P1J9
Cellular localization: Nucleus .
Background: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009],