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NUT rabbit pAb
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ES8833
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50 µL $148.00
100 µL $248.00
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Overview

Product name: NUT rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Protein NUT (Nuclear protein in testis)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from human NUT. at AA range: 1082-1131
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 63kD
GeneID: 256646
Human Swiss-Prot No: Q86Y26
Cellular localization: Cytoplasm . Nucleus . Shuttles between nucleus and cytoplasm. .
Background: disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with BRD4 which produces a BRD4-NUT fusion protein.,disease:A chromosomal aberration involving NUT is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with BRD3 which produces a BRD3-NUT fusion protein.,PTM:Phosphorylation on Ser-1026, Ser-1029 or Ser-1031 is important for cytoplasmic export.,similarity:Belongs to the FAM22 family.,subcellular location:Shuttles between nucleus and cytoplasm.,tissue specificity:Specifically expressed in testis.,