PARP-1 (Acetyl-K521) rabbit pAb

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PARP-1 (Acetyl-K521) rabbit pAb

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ES8828

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PARP-1 (Acetyl-K521) rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)
Source:	Rabbit
Dilutions:	wb dilution 1:1000
Immunogen:	Synthesized Acetyl peptide derived from human PARP-1. at AA range: K521
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
GeneID:	142
Human Swiss-Prot No:	P09874
Cellular localization:	Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of DNA damage. .
Background:	This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

Western Blot analysis of 1,mouse-heart 2,mouse-brain cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
Western Blot analysis of 1,293t 2,mouse-brain cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)