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Frizzled-4 rabbit pAb
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ES8800
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Frizzled-4 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Frizzled-4 (Fz-4;hFz4;FzE4;CD antigen CD344)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 11-60
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 8322
Human Swiss-Prot No: Q9ULV1
Cellular localization: Cell membrane ; Multi-pass membrane protein .
Background: frizzled class receptor 4(FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008],