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GRB7 rabbit pAb
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ES8778
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GRB7 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Growth factor receptor-bound protein 7 (B47;Epidermal growth factor receptor GRB-7;GRB7 adapter protein)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 30-100
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 2886
Human Swiss-Prot No: Q14451
Cellular localization: Cytoplasm . Cell junction, focal adhesion . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic granule . Cell projection . Predominantly cytoplasmic. Detected in stress granules, where mRNA is stored under stress conditions. .
Background: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011],