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EphB3 rabbit pAb
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ES8777
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50 µL $148.00
100 µL $248.00
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Overview

Product name: EphB3 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: Ephrin type-B receptor 3 (EC 2.7.10.1;EPH-like tyrosine kinase 2;EPH-like kinase 2;Embryonic kinase 2;EK2;hEK2;Tyrosine-protein kinase TYRO6)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 650-700
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 2049
Human Swiss-Prot No: P54753
Cellular localization: Cell membrane ; Single-pass type I membrane protein . Cell projection, dendrite .
Background: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010],