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ASPP1 rabbit pAb
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ES8768
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50 µL $148.00
100 µL $248.00
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Overview

Product name: ASPP1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 630-680
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 23368
Human Swiss-Prot No: Q96KQ4
Cellular localization: Cytoplasm . Nucleus . Predominantly cytoplasmic. Some fraction is nuclear.
Background: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008],