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Napsin A rabbit pAb
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ES8747
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Napsin A rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Napsin-A (EC 3.4.23.-;Aspartyl protease 4;ASP4;Asp 4;Napsin-1;TA01/TA02)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 191-240
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 9476
Human Swiss-Prot No: O96009
Cellular localization: Secreted .
Background: This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016],