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BMP-9 rabbit pAb
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ES8713
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50 µL $148.00
100 µL $248.00
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Overview

Product name: BMP-9 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: Growth/differentiation factor 2 (GDF-2;Bone morphogenetic protein 9;BMP-9)
Source: Rabbit
Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 371-420
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID: 2658
Human Swiss-Prot No: Q9UK05
Cellular localization: Secreted .
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],