| Product name: |
Mac-2BP rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
Galectin-3-binding protein (Basement membrane autoantigen p105) (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (MAC2BP) (Mac-2 BP) (Tumor-associated antigen 90K) |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: |
Synthetic peptide from human protein at AA range: 100-160 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
65kD |
| GeneID: |
3959 |
| Human Swiss-Prot No: |
Q08380 |
| Cellular localization: |
Secreted . Secreted, extracellular space, extracellular matrix . |
| Background: |
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008], |
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