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FAM48A rabbit pAb
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ES8546
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50 µL $148.00
100 µL $248.00
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Overview

Product name: FAM48A rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: FAM48A C13orf19 FP757
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 85kD
GeneID: 55578
Human Swiss-Prot No: Q8NEM7
Cellular localization: Nucleus .
Background: function:Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.,similarity:Belongs to the FAM48 family.,subunit:Interacts with MAPK14.,tissue specificity:Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.,