ETBR rabbit pAb

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ETBR rabbit pAb

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ES8504

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	ETBR rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	Endothelin B receptor (ET-B;ET-BR;Endothelin receptor non-selective type)
Source:	Rabbit
Dilutions:	IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Immunogen:	Synthesized peptide derived from ETBR at AA range: 31-80
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	50kD
GeneID:	1910
Human Swiss-Prot No:	P24530
Cellular localization:	Cell membrane ; Multi-pass membrane protein. internalized after activation by endothelins. .
Background:	The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],

Western Blot analysis of Hela cells using ETBR Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded Human placenta. 1, Antibody was diluted at 1:200(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).