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IL-17RB rabbit pAb
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ES8499
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50 µL $148.00
100 µL $248.00
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Overview

Product name: IL-17RB rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor)
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from IL-17RB at AA range: 251-300
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 55kD
GeneID: 55540
Human Swiss-Prot No: Q9NRM6
Cellular localization: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
Background: The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008],