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BMP-10 rabbit pAb
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ES8468
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50 µL $148.00
100 µL $248.00
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Overview

Product name: BMP-10 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: bone morphogenetic protein 10
Source: Rabbit
Dilutions: WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthesized peptide derived from BMP-10 at AA range: 361-410
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 48kD
GeneID: 27302
Human Swiss-Prot No: O95393
Cellular localization: Secreted .
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016],