Product name: |
CKR-6 rabbit pAb |
Reactivity: |
Human;Rat;Mouse; |
Alternative Names: |
CCR6; CKRL3; CMKBR6; GPR29; STRL22; C-C chemokine receptor type 6; C-C CKR-6; CC-CKR-6; CCR-6; Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD196 |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CCR6. AA range:1-50 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
42kD |
GeneID: |
1235 |
Human Swiss-Prot No: |
P51684 |
Cellular localization: |
Cell membrane ; Multi-pass membrane protein . Cell surface . |
Background: |
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008], |