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Axl rabbit pAb
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ES8372
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Axl rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from Axl . at AA range: 630-710
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 130kD
GeneID: 558
Human Swiss-Prot No: P30530
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],