| Product name: |
CD269 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
TNFRSF17; BCM; BCMA; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from the Internal region of human CD269. |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
20kD |
| GeneID: |
608 |
| Human Swiss-Prot No: |
Q02223 |
| Cellular localization: |
Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Perinuclear Golgi-like structures. |
| Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008], |
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