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Topo IIIα rabbit pAb
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ES8351
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Topo IIIα rabbit pAb
Reactivity: Human;Mouse
Alternative Names: TOP3A; TOP3; DNA topoisomerase 3-alpha; DNA topoisomerase III alpha
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from Topo IIIα . at AA range: 350-430
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 115kD
GeneID: 7156
Human Swiss-Prot No: Q13472
Cellular localization: Mitochondrion matrix .
Background: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],