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GASP-1 rabbit pAb
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ES8093
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GASP-1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: GPRASP1; GASP; KIAA0443; G-protein coupled receptor-associated sorting protein 1; GASP-1
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GASP1. AA range:741-790
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 157kD
GeneID: 9737
Human Swiss-Prot No: Q5JY77
Cellular localization: Cytoplasm .
Background: This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010],