Product name: |
NCKX1 rabbit pAb |
Reactivity: |
Human;Rat;Mouse; |
Alternative Names: |
SLC24A1; KIAA0702; NCKX1; Sodium/potassium/calcium exchanger 1; Na(+)/K(+)/Ca(2+)-exchange protein 1; Retinal rod Na-Ca+K exchanger |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human SLC24A1. AA range:154-203 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
125kD |
GeneID: |
9187 |
Human Swiss-Prot No: |
O60721 |
Cellular localization: |
Cell membrane ; Multi-pass membrane protein . |
Background: |
This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. The encoded protein plays an important role in sodium/calcium exchange in retinal rod and cone photoreceptors by mediating the extrusion of one calcium ion and one potassium ion in exchange for four sodium ions. Mutations in this gene may play a role in congenital stationary night blindness. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011], |