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REPS1 rabbit pAb
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ES7799
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50 µL $148.00
100 µL $248.00
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Overview

Product name: REPS1 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: REPS1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human REPS1. AA range:597-646
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 80kD
GeneID: 85021
Human Swiss-Prot No: Q96D71
Cellular localization: Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.
Background: This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],