| Product name: |
Rab11-FIP1 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
RAB11FIP1; RCP; Rab11 family-interacting protein 1; Rab11-FIP1; Rab-coupling protein |
| Source: |
Rabbit |
| Dilutions: |
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
Synthesized peptide derived from Rab11-FIP1 . at AA range: 70-150 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Molecular Weight: |
137kD |
| GeneID: |
80223 |
| Human Swiss-Prot No: |
Q6WKZ4 |
| Cellular localization: |
Recycling endosome . Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC).; [Isoform 2]: Cytoplasmic vesicle, phagosome membrane. Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2). |
| Background: |
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013], |
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