| Product name: |
14-3-3 ζ/δ (phospho Thr232) rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
YWHAZ; 14-3-3 protein zeta/delta; Protein kinase C inhibitor protein 1; KCIP-1 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human 14-3-3 zeta/delta around the phosphorylation site of Thr232. AA range:196-245 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
28kD |
| GeneID: |
7534 |
| Human Swiss-Prot No: |
P63104 |
| Cellular localization: |
Cytoplasm . Melanosome . Located to stage I to stage IV melanosomes. |
| Background: |
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008], |
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