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Wee 1 (phospho Ser53) rabbit pAb
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ES7516
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Wee 1 (phospho Ser53) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human WEE1 around the phosphorylation site of Ser53. AA range:19-68
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 72kD
GeneID: 7465
Human Swiss-Prot No: P30291
Cellular localization: Nucleus.
Background: WEE1 G2 checkpoint kinase(WEE1) Homo sapiens This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008],