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Vimentin (phospho Ser56) rabbit pAb
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ES7507
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Vimentin (phospho Ser56) rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: VIM; Vimentin
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Vimentin around the phosphorylation site of Ser56. AA range:31-80
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 54kD
GeneID: 7431
Human Swiss-Prot No: P08670
Cellular localization: Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .
Background: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],