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Tuberin rabbit pAb
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ES7452
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Tuberin rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Tuberin. AA range:947-996
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 210kD
GeneID: 7249
Human Swiss-Prot No: P49815
Cellular localization: Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],