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Cadherin-23 rabbit pAb
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ES7147
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Cadherin-23 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin
Source: Rabbit
Dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CDH23. AA range:61-110
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 370kD
GeneID: 64072
Human Swiss-Prot No: Q9H251
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013],